The BC senior has Ewing's Sarcoma, a tumor often found in bone or soft tissue.
Herzlich released a statement that he was focusing on his senior season for the Eagles when he was "shocked" by the news but is determined to face his "toughest opponent yet."
"When people think of Mark Herzlich, they think of a fearless individual who is always ready to take on a tough opponent. His integrity, determination and focus are unmatched. I know he will face this challenge with that same attitude," BC coach Frank Spaziani said, per ESPN.
Last season Herzlich was a finalist for the Butkus Award, which is given to the nation's top linebacker. He had 110 tackles, six interceptions, two forced fumbles and two fumble recoveries for the Eagles.
Many are offering their thoughts and prayers through Twitter for Herzlich:
MHsports Get well soon Mark Herzlich
http://bit.ly/F9Rg8 schadjoe Devastating news. BC All American Mark Herzlich has Ewings Sarcoma, a soft tissue cancer. Pray for Mark. MonsterSeats Saying a pray for BC linebacker Mark Herzlich, who is now battling cancer. Terrible situation. dice_j bc eagles fans: pray for mark herzlich... BostonCollege All good wishes to BC linebacker Mark Herzlich, diagnosed with cancer: http://bit.ly/HM85v billg Our thoughts & prayers are with BC linebacker Mark Herzlich - diagnosed with cancer - http://bit.ly/5jjLk BREBERGG If I were cancer I'd b scared shitless of mark herzlich. Wishing him all the best.. Larry_Jensen Boston College's Mark Herzlich was diagnosed with cancer. He was the ACC' Defensive Player of the Year. Poor kid, I sure hope he beats it.